Clemson at Syracuse odds, picks and prediction

Skip Snow
Sportsbook Wire

The No. 25 Clemson Tigers (3-2, 2-1 ACC) visit the Syracuse Orange (3-3, 0-2) in a Friday ACC Atlantic Division showdown. Kickoff at the Carrier Dome is slated for 7 p.m. ET. Below, we look at the Clemson vs. Syracuse odds and lines, and make our expert college football picks, predictions and bets.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

Clemson's offense has continued to struggle. The Tigers come into this contest having played in three straight games decided by one score (which was followed by an off week). The most recent close tussle was a 19-13 victory over Boston College Oct. 2. Clemson has cranked out just 324.2 yards per game, which ranks 117th in the nation.

Syracuse has played in three straight games decided by 3 points each. The most recent was a 40-37 overtime loss to now-No. 16 Wake Forest Oct. 9. The Orange piled up a season-high 354 rushing yards and 514 total yards in that contest. For the season, the SU rushing attack ranks 10th (244.5 yards per game).

Clemson at Syracuse odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports' betting odds for a full list. Lines last updated at 3:46 a.m. ET.

  • Money line: Clemson -600 (bet $600 to win $100) | Syracuse +420 (bet $100 to win $420)
  • Against the spread (ATS): Clemson -13.5 (-110) | Syracuse +13.5 (-110)
  • Over/Under (O/U): 44.5 (O: -112 | U: -108)

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Clemson at Syracuse odds, lines, picks and predictions


Clemson 31, Syracuse 14

Money line

PASS on the gulf in prices here. Figure the true odds being well bracketed on both ends.

Against the spread

Look for a talented Clemson to be a bit sharper all around coming off a bye week. The Tigers are strong enough in the front seven to spell problems for a Syracuse offense which has leaned successfully on the run.

The Orange have piled up 22 sacks but in chunks against outmatched foes. Peg Clemson QB D.J. Uiagalelei as being undervalued a tad here.

TAKE THE TIGERS -13.5 (-110).


The Under is 4-1 across the last five meetings between the Tigers and Orange. That's the lean for this Friday nighter featuring a struggling CU offense and a solid SU defense.

BACK THE UNDER 44.5 (-108).

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